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HIV prevention — USMLE Step 3 MCQ

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ModerateAmbulatory Medicine / Primary CareHIV preventionUSMLE Step 3

A 27-year-old man requests HIV prevention counseling. He has sex with men, uses condoms inconsistently, and had rectal gonorrhea 2 months ago. HIV antigen-antibody testing is negative today and creatinine is normal. Hepatitis B serologies are pending. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Offer HIV preexposure prophylaxis with baseline monitoring

Persons at increased risk of HIV acquisition should be offered effective PrEP after HIV-negative status and baseline safety assessment.

Reference: USPSTF HIV PrEP recommendation; CDC PrEP guidance