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Gout treat-to-target follow-up — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Gout treat-to-target follow-upUSMLE Step 3

A 62-year-old man with gout started allopurinol and low-dose colchicine 2 months ago. Serum urate decreased from 9.6 to 7.1 mg/dL, and he has had no flares. Kidney function is stable. Which of the following would you recommend at the follow-up visit?

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Correct answer: D — Titrate allopurinol toward a serum urate target below 6 mg/dL

Treat-to-target urate-lowering therapy aims for serum urate below 6 mg/dL in most patients with gout.

Reference: ACR gout guideline