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Hepatocellular carcinoma surveillance — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Hepatocellular carcinoma surveillanceUSMLE Step 3

A 59-year-old man with cirrhosis from treated hepatitis C comes to establish care. He has no ascites, no encephalopathy, and no history of hepatocellular carcinoma. Which of the following is the most appropriate screening recommendation?

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Correct answer: BLiver ultrasonography with or without alpha-fetoprotein every 6 months

Patients with cirrhosis require surveillance for hepatocellular carcinoma, typically every 6 months.

Reference: AASLD hepatocellular carcinoma surveillance guidance