A 39-year-old woman becomes tachycardic and hypotensive shortly after induction of anesthesia with succinylcholine. Temperature rises to 40.2 C,

Question

A 39-year-old woman becomes tachycardic and hypotensive shortly after induction of anesthesia with succinylcholine. Temperature rises to 40.2 C, end-tidal CO2 increases sharply, and generalized rigidity is noted. Which of the following is the most likely explanation for this patient's findings?

Accepted Answer

Uncontrolled calcium release from skeletal muscle sarcoplasmic reticulum

Answer

Histamine release from vancomycin infusion

Answer

IgA deficiency causing transfusion reaction

Answer

Acute adrenal hemorrhage

Answer

Vagal stimulation from intubation

Malignant hyperthermia — USMLE Step 3 MCQ

A 39-year-old woman becomes tachycardic and hypotensive shortly after induction of anesthesia with succinylcholine. Temperature rises to 40.2 C, end-tidal CO2 increases sharply, and generalized rigidity is noted. Which of the following is the most likely explanation for this patient's findings?