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Hyperprolactinemia — USMLE Step 3 MCQ

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ModerateOB/GYN (prenatal care, contraception, screening)HyperprolactinemiaUSMLE Step 3

A 35-year-old woman has secondary amenorrhea for 5 months. Pregnancy test is negative. Prolactin is 82 ng/mL, TSH is normal, and she has galactorrhea. She takes no antipsychotics. Which of the following is the most appropriate at this time?

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Correct answer: CMRI of the pituitary

Hyperprolactinemia with amenorrhea and galactorrhea after excluding pregnancy and hypothyroidism warrants pituitary imaging.

Reference: Endocrine Society hyperprolactinemia guideline