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Diabetic peripheral neuropathy — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Diabetic peripheral neuropathyUSMLE Step 3

A 68-year-old woman with diabetes has burning foot pain and loss of monofilament sensation. A1c is 7.5%. She has no ulcer. Pulses are present. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BStart duloxetine and institute daily foot care education

Painful diabetic peripheral neuropathy can be treated with duloxetine, and foot care education reduces ulcer risk.

Reference: ADA Standards of Care in Diabetes 2026