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Chronic limb-threatening ischemia — USMLE Step 3 MCQ

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HardSurgery (post-operative, follow-up)Chronic limb-threatening ischemiaUSMLE Step 3

A patient with diabetes has a nonhealing forefoot ulcer, toe pressure 22 mm Hg and multilevel femoropopliteal and tibial disease. There is no uncontrolled infection, and usable autogenous vein is present. What is the best overarching management strategy?

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Correct answer: CPlan limb-salvage revascularization to restore in-line flow to the ulcer

The best answer is “Plan limb-salvage revascularization to restore in-line flow to the ulcer”. This is chronic limb-threatening ischemia. Revascularization planning integrates anatomy, conduit, wound severity, infection and patient risk to restore perfusion for healing and limb preservation; medical and wound care remain essential but are not substitutes.

Reference: 2024 ACC/AHA Guideline for Lower Extremity Peripheral Artery Disease: https://www.heart.org/-/media/PHD-Files-2/Science-News/2/2024/2024-PAD-guideline-slide-set.pdf