A randomized trial reports that a new medication reduces annual stroke incidence from 4% to 2% compared with placebo. The investigator asks for the

Question

A randomized trial reports that a new medication reduces annual stroke incidence from 4% to 2% compared with placebo. The investigator asks for the absolute difference in event rates. Which of the following is the most likely diagnosis?

Accepted Answer

Absolute risk reduction of 2 percentage points

Answer

Sensitivity of 50%

Answer

Relative risk of 2

Answer

Number needed to harm of 2

Answer

Positive predictive value of 2%

Absolute risk reduction — USMLE Step 3 MCQ

A randomized trial reports that a new medication reduces annual stroke incidence from 4% to 2% compared with placebo. The investigator asks for the absolute difference in event rates. Which of the following is the most likely diagnosis?