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Polymyalgia rheumatica — USMLE Step 3 MCQ

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ModerateInternal Medicine (chronic management)Polymyalgia rheumaticaUSMLE Step 3

A 65-year-old woman has proximal muscle stiffness and aching in the shoulders and hips for 2 months. Symptoms are worse in the morning and improve during the day. ESR is 78 mm/h, creatine kinase is normal, and there is no objective weakness. Which of the following is the most likely diagnosis?

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Correct answer: DPolymyalgia rheumatica

Proximal girdle pain and stiffness with elevated inflammatory markers and normal CK in an older adult suggest polymyalgia rheumatica.

Reference: ACR/EULAR polymyalgia rheumatica guidance