Solitary pulmonary nodule — ABIM Board MCQ
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Correct answer: A — Obtain FDG-PET/CT for further nodule characterization
The best answer is “Obtain FDG-PET/CT for further nodule characterization”. For a solid nodule larger than 8 mm with low-to-moderate malignancy probability, functional imaging with PET is appropriate before choosing surveillance or biopsy. Immediate surgery is usually reserved for high probability or strongly positive findings after preference discussion. Chest radiography, eosinophils and bronchoprovocation do not characterize cancer risk.
Reference: American College of Chest Physicians Pulmonary Nodule Evaluation Guideline: https://pmc.ncbi.nlm.nih.gov/articles/PMC3749714/