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Hypercalcemia from primary hyperparathyroidism — ABFM Board MCQ

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ModerateEndocrine/MetabolicHypercalcemia from primary hyperparathyroidismABFM Board

A 66-year-old woman has fatigue and recurrent kidney stones. Calcium is 11.4 mg/dL on repeat testing, phosphorus is low, and parathyroid hormone is elevated. Which of the following is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Primary hyperparathyroidism

Elevated calcium with inappropriately elevated parathyroid hormone and kidney stones is most consistent with primary hyperparathyroidism.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html