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Subclinical hypothyroidism — ABFM Board MCQ

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ModerateEndocrine/MetabolicSubclinical hypothyroidismABFM Board

A 61-year-old woman has TSH of 6.8 mIU/L found during evaluation of mild fatigue. Free T4 is normal and thyroid peroxidase antibody is negative. She has no goiter. Which of the following is the most appropriate next step?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Repeat TSH before deciding on treatment

Mild subclinical hypothyroidism often warrants repeat testing and individualized decision-making rather than automatic treatment.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html