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Nonalcoholic fatty liver disease — ABFM Board MCQ

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ModerateGI/HepatologyNonalcoholic fatty liver diseaseABFM Board

A 49-year-old man with obesity, type 2 diabetes, and hypertriglyceridemia has mildly elevated ALT and AST on two occasions. He drinks one beer weekly and hepatitis B and C tests are negative. Which of the following is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Nonalcoholic fatty liver disease

Metabolic risk factors with persistent mild transaminase elevation and minimal alcohol use are typical of nonalcoholic fatty liver disease.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html