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Initial type 2 diabetes therapy — ABFM Board MCQ

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EasyEndocrine/MetabolicInitial type 2 diabetes therapyABFM Board

A 53-year-old man is newly diagnosed with type 2 diabetes. A1c is 7.8%, eGFR is 82 mL/min/1.73 m2, and he has no heart failure or established atherosclerotic disease. He is motivated to change diet and activity. Which of the following is the most appropriate initial treatment?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BMetformin plus lifestyle modification

Metformin with lifestyle modification remains an appropriate initial treatment for many adults with uncomplicated type 2 diabetes and preserved kidney function.

Reference: ADA Standards of Care in Diabetes 2026: https://professional.diabetes.org/standards-of-care