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Acute pyelonephritis — ABFM Board MCQ

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ModerateUrology/RenalAcute pyelonephritisABFM Board

A 31-year-old woman has fever, flank pain, nausea, and dysuria. Urinalysis shows pyuria and bacteriuria. She is able to tolerate oral medications and is not pregnant. Which of the following is the most appropriate next step?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Urine culture and outpatient oral antibiotics with appropriate initial coverage

Pyelonephritis requires urine culture and prompt antibiotics; stable nonpregnant patients may be treated as outpatients with suitable regimens.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html