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Polypharmacy — ABFM Board MCQ

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ModerateGeriatricsPolypharmacyABFM Board

An 84-year-old man has dizziness and constipation. His medications include amitriptyline, oxybutynin, diphenhydramine, lisinopril, and metformin. Cognition has worsened since sleep medication was added. Which of the following is the most appropriate next step?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Deprescribe anticholinergic medications when possible

Anticholinergic burden contributes to confusion, constipation, falls, and urinary retention in older adults; deprescribing is appropriate.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html