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Celiac disease — ABFM Board MCQ

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ModerateGI/HepatologyCeliac diseaseABFM Board

A 29-year-old woman has chronic bloating, loose stools, iron deficiency anemia, and a pruritic vesicular rash on the elbows. Her mother has autoimmune thyroid disease. Which of the following is the most appropriate next step?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CTissue transglutaminase IgA with total IgA level

Chronic diarrhea, iron deficiency, and dermatitis herpetiformis suggest celiac disease; IgA tissue transglutaminase with total IgA is an appropriate initial test.

Reference: American Family Physician clinical reviews and AAFP guidance: https://www.aafp.org/pubs/afp.html