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Serotonin syndrome — ABEM Board MCQ

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ModerateToxicologySerotonin syndromeABEM Board

A 23-year-old woman taking sertraline arrives after starting linezolid. Triage acuity is ESI 2; T 102.0 F, BP 156/88 mm Hg, HR 132/min. She is agitated with diaphoresis, inducible clonus, hyperreflexia, and diarrhea. Which of the following is the most likely diagnosis?

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Correct answer: CSerotonin syndrome

Clonus, hyperreflexia, autonomic instability, diarrhea, and serotonergic drug interaction support serotonin syndrome.

Reference: ACMT toxicology guidance