Posterior cortical atrophy — SCE Neurology MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCognitive NeurologyPosterior cortical atrophySCE Neurology

A 79-year-old woman presented with progressive visuospatial difficulty, dressing apraxia and getting lost. On examination, visual acuity was normal but simultanagnosia was present. Initial investigations showed: MRI showed parieto-occipital atrophy. Where is the most likely anatomical localisation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — parieto-occipital association cortex

parieto-occipital association cortex is the best answer because the vignette describes Posterior cortical atrophy: higher visual dysfunction with posterior atrophy indicates posterior cortical atrophy. Neuromuscular junction is plausible in a neighbouring presentation, but the chronology, examination or investigation pattern does not match the key discriminator here. Superior sagittal sinus and Subarachnoid space are less appropriate because they would require different localisation, timing or test findings; Dominant temporal lobe would fit a different syndrome. Clinical pearl: ocular disease would reduce acuity rather than cause cortical visual signs.

Reference: NICE NG97; consensus criteria for dementia syndromes