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Becker muscular dystrophy — SCE Neurology MCQ

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HardNeuromuscularBecker muscular dystrophySCE Neurology

A patient has adolescent-onset calf hypertrophy and proximal weakness, remains ambulant in adulthood, and has an in-frame dystrophin deletion. What is the diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EBecker muscular dystrophy with partially functional dystrophin

The best answer is “Becker muscular dystrophy with partially functional dystrophin”. UK stroke guidance supports urgent vascular imaging and reperfusion selection, short-course dual antiplatelet therapy for eligible minor stroke or high-risk TIA, decompression for life-threatening swelling, and secondary prevention matched to mechanism. The alternatives “Duchenne muscular dystrophy with absent dystrophin expression”, “Limb-girdle muscular dystrophy caused by sarcoglycan dysfunction”, “Facioscapulohumeral muscular dystrophy with scapular winging”, “Oculopharyngeal muscular dystrophy with ptosis and dysphagia” are clinically adjacent possibilities, but they do not match the defining chronology, localisation, physiology, investigation result or UK management sequence in this stem.

Reference: National Clinical Guideline for Stroke: acute care: https://www.strokeguideline.org/chapter/acute-care/