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Balo concentric sclerosis — SCE Neurology MCQ

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HardMSBalo concentric sclerosisSCE Neurology

A 55-year-old woman presented with rapid hemiparesis with MRI showing alternating concentric rings. On examination, there was dysarthria and brisk reflexes. Initial investigations showed: MRI diffusion and enhancement formed lamellated rings within a white-matter lesion. What is the most appropriate management?

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Correct answer: ATreat as a disabling demyelinating relapse with high-dose methylprednisolone after excluding infection

Concentric demyelinating rings are characteristic of Baló concentric sclerosis, a tumefactive demyelinating syndrome. After infection has been reasonably excluded, a disabling acute presentation is managed as a demyelinating relapse with high-dose corticosteroids and specialist follow-up.

Reference: NICE NG220, multiple sclerosis in adults: https://www.nice.org.uk/guidance/ng220/chapter/Recommendations