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Pre-eclampsia prevention — DRCOG MCQ

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ModerateAntenatal CarePre-eclampsia preventionDRCOG

A 39-year-old nulliparous woman attends her 10-week booking appointment. Her BMI is 36 kg/m² and her mother had pre-eclampsia. Her blood pressure and urinalysis are normal. What is the most appropriate management?

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Correct answer: A — Start aspirin 75 to 150 mg daily from 12 weeks until birth

NICE recommends aspirin from 12 weeks for women at high risk of pre-eclampsia, and also for those with more than one moderate risk factor such as nulliparity, age 40 or over, obesity or family history. Labetalol is for established hypertension rather than prophylaxis. Routine 24-hour urine collection is not used for screening. Thromboprophylaxis is based on VTE risk, not pre-eclampsia prevention alone.

Reference: NICE NG133