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Implant and enzyme induction — DRCOG MCQ

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ModerateContraceptionImplant and enzyme inductionDRCOG

A 26-year-old woman has a contraceptive implant and is started on rifampicin for tuberculosis. She asks whether her implant is still reliable. She is sexually active. What would you advise?

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Correct answer: C — Use additional contraception and discuss a method unaffected by enzyme induction

Rifampicin is a potent enzyme inducer and can reduce implant effectiveness, so additional contraception and a method unaffected by enzyme induction, such as copper IUD or injectable, should be discussed. Reassurance would be incorrect. Removing the implant without replacement advice increases pregnancy risk. Ulipristal is not used as weekly ongoing contraception.

Reference: FSRH Drug Interactions with Hormonal Contraception; FSRH UKMEC