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Family history of ovarian cancer — DRCOG MCQ

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HardGynaecological OncologyFamily history of ovarian cancerDRCOG

A 38-year-old woman asks about ovarian cancer risk. Her mother and maternal grandmother both had epithelial ovarian cancer before age 60. She has no symptoms. When should this patient be referred?

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Correct answer: DRefer for genetics assessment

A strong family history of ovarian cancer warrants genetics assessment for hereditary cancer syndromes such as BRCA-related disease. CA125 surveillance alone is not an adequate primary-care strategy. Being asymptomatic does not remove inherited risk. Risk-reducing options and screening limitations should be discussed in specialist services.

Reference: NICE CG164; NICE CKS ovarian cancer