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Chickenpox exposure in pregnancy — DRCOG MCQ

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ModerateAntenatal CareChickenpox exposure in pregnancyDRCOG

A 32-year-old woman who is 18 weeks pregnant reports significant household exposure to chickenpox. She is unsure whether she had chickenpox as a child and feels well. There is no rash. What is the most appropriate investigation?

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Correct answer: E — Check varicella-zoster IgG urgently

After significant chickenpox exposure in pregnancy, the first step is to establish immunity with varicella-zoster IgG if history is uncertain. Antiviral treatment is used for established infection in selected circumstances rather than immediately after exposure. MMR does not protect against varicella and is contraindicated in pregnancy. If she is non-immune, post-exposure prophylaxis should be considered through maternity or infectious diseases pathways.

Reference: RCOG Green-top Guideline No. 13; UKHSA guidance