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Train-of-four fade — FRCA Primary MCQ

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ModeratePhysicsTrain-of-four fadeFRCA Primary

Four twitches with fade occur after vecuronium. What is the most likely explanation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DResidual non-depolarising neuromuscular block

Train-of-four fade indicates residual non-depolarising neuromuscular blockade at the neuromuscular junction. Mapleson D is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Uneven alveolar emptying is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Infrared gas analyser is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Airway laser fire risk is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA physics and measurement, the safest answer is the one that follows the underlying physical principle and the limitations of the device.

Reference: Davis and Kenny Basic Physics and Measurement in Anaesthesia; RCoA Primary FRCA syllabus