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Pregnancy desaturation — FRCA Primary MCQ

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ModeratePhysiologyPregnancy desaturationFRCA Primary

A term pregnant patient desaturates rapidly during rapid sequence induction. What is the most likely explanation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AHigh oxygen consumption and low FRC shorten safe apnoea time

Pregnancy reduces FRC and increases oxygen consumption. Hypoxic pulmonary vasoconstriction diverts blood flow is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Central chemoreceptors respond to CSF hydrogen ion concentration is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Right ventricular afterload rises with pulmonary vascular resistance is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Small myelinated fibres block relatively early is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA physiology, the correct answer is usually the variable that best explains the observed change in the anaesthetised patient.

Reference: West's Respiratory Physiology; Ganong Review of Medical Physiology; Primary FRCA textbooks