Airway resistance — FRCA Primary MCQ
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Correct answer: E — Ventilation of poorly perfused alveoli increases dead space
Small reductions in airway radius markedly increase resistance. Hypothermia shifts the oxyhaemoglobin curve left is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Pain and temperature ascend in the spinothalamic tract is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. ADH inserts aquaporin-2 channels in collecting ducts is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Central chemoreceptors respond to CSF hydrogen ion concentration is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA physiology, the correct answer is usually the variable that best explains the observed change in the anaesthetised patient.
Reference: West's Respiratory Physiology; Ganong Review of Medical Physiology; Primary FRCA textbooks