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Alveolar gas equation — FRCA Primary MCQ

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EasyPhysiologyAlveolar gas equationFRCA Primary

A hypoventilating patient on air has PaCO2 8.0 kPa and low alveolar oxygen tension. What is the most likely explanation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BRaised PaCO2 lowers alveolar oxygen tension

The alveolar gas equation links increased PaCO2 with reduced PAO2. Hypoxic pulmonary vasoconstriction diverts blood flow is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Increased preload increases stroke volume through fibre stretch is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Aldosterone increases sodium reabsorption and potassium secretion is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Acidosis shifts the oxyhaemoglobin curve right is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA physiology, the correct answer is usually the variable that best explains the observed change in the anaesthetised patient.

Reference: West's Respiratory Physiology; Ganong Review of Medical Physiology; Primary FRCA textbooks