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Renal autoregulation — FRCA Primary MCQ

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EasyPhysiologyRenal autoregulationFRCA Primary

Renal blood flow changes little as MAP falls moderately under anaesthesia. What is the most likely explanation?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BRenin rises with reduced afferent arteriolar pressure

Myogenic response and tubuloglomerular feedback maintain renal blood flow over a range. Reduced haemoglobin lowers arterial oxygen content is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Closing capacity exceeding FRC causes airway closure is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Pain and temperature ascend in the spinothalamic tract is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Raised PaCO2 lowers alveolar oxygen tension is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA physiology, the correct answer is usually the variable that best explains the observed change in the anaesthetised patient.

Reference: West's Respiratory Physiology; Ganong Review of Medical Physiology; Primary FRCA textbooks