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Sevoflurane low solubility — FRCA Primary MCQ

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ModeratePharmacologySevoflurane low solubilityFRCA Primary

A child loses consciousness rapidly during inhalational induction with a low blood-gas solubility agent. Which drug is most likely?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Sevoflurane

Sevoflurane has relatively low blood-gas solubility and is well tolerated for inhalational induction. Hydrocortisone is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Noradrenaline is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Adenosine is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. Magnesium sulphate is less appropriate because it would fit a different clinical clue or a separate anaesthetic problem. In Primary FRCA pharmacology, link the clinical effect to the receptor, distribution or elimination mechanism rather than memorising isolated facts.

Reference: Peck, Hill & Williams Pharmacology for Anaesthesia and Intensive Care; BNF; Primary FRCA textbooks