Influenza vaccination (elderly) — MCCQE Part 1 MCQ

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ModeratePreventive MedicineInfluenza vaccination (elderly)MCCQE Part 1

A 65-year-old man with COPD, HTN, DM, and depression asks about influenza vaccination. Per NACI 2025-2026, which formulation is most appropriate?

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Correct answer: C — High-dose or adjuvanted inactivated influenza vaccine

NACI 2025-2026: high-dose or adjuvanted IIV preferred for adults >=65. Superior immunogenicity. LAIV contraindicated in immunocompromised/chronic diseases. All adults with chronic conditions should receive influenza vaccine annually.

Reference: NACI Influenza Statement 2025-2026