Smoking cessation — MCCQE Part 1 MCQ

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ModeratePreventive MedicineSmoking cessationMCCQE Part 1

A 55-year-old woman who smokes 10/day x 10 years wants to quit. Failed with willpower alone. Motivated. Most effective pharmacological intervention?

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Correct answer: C — Combination NRT (patch + gum/lozenge) or varenicline

Combination NRT or varenicline most effective (~double quit rates vs placebo). E-cigarettes not recommended first-line. All pharmacotherapy should be combined with behavioural support. CTFPHC strongly recommends asking about tobacco use.

Reference: CAN-ADAPTT / CTFPHC Tobacco 2025