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HPV vaccination — MCCQE Part 1 MCQ

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EasyPreventive MedicineHPV vaccinationMCCQE Part 1

A 19-year-old man living with HIV has never received human papillomavirus vaccine. His HIV is treated, and he has no contraindication to vaccination. According to current NACI guidance, which schedule should be recommended?

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Correct answer: C — Give a three-dose 9-valent HPV vaccine series

NACI recommends a three-dose nonavalent HPV vaccine series for people who are immunocompromised or living with HIV, regardless of the shorter age-based schedule used for immunocompetent people. The minimum intervals are four weeks between doses one and two, twelve weeks between doses two and three, and twenty-four weeks between the first and last doses. Treated HIV is not a reason to defer vaccination. A single dose is the routine schedule for immunocompetent people aged 9 to 20, and two doses are used for immunocompetent adults beginning at age 21; neither shorter schedule applies to this patient.

Reference: National Advisory Committee on Immunization, updated HPV vaccine recommendations, July 24, 2024: https://www.canada.ca/en/public-health/services/publications/vaccines-immunization/national-advisory-committee-immunization-summary-updated-recommendations-hpv-vaccines.html