Bipolar I (acute mania) — MCCQE Part 1 MCQ
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Correct answer: D — Mood stabiliser (lithium) or atypical antipsychotic (quetiapine/olanzapine)
Acute mania: CANMAT recommends lithium, valproate, or atypical antipsychotic first-line. Antidepressant without mood stabiliser CONTRAINDICATED — can worsen mania. Likely requires hospitalisation.
Reference: CANMAT Bipolar 2024