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Post-streptococcal GN — MCCQE Part 1 MCQ

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ModerateBlood in UrinePost-streptococcal GNMCCQE Part 1

A 7-year-old girl has cola-coloured urine, periorbital oedema, and BP 130/85 x 1 week. Sore throat 2 weeks ago treated with acetaminophen only. Dysmorphic RBCs, red cell casts. C3 low, ASO elevated. Most likely diagnosis?

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Correct answer: C — Post-streptococcal glomerulonephritis

Nephritic syndrome post-streptococcal pharyngitis (1-3 week latency) + low C3 + elevated ASO = PSGN. Management: supportive (sodium/fluid restriction, antihypertensives). C3 normalises in 6-8 weeks.

Reference: CPS Paediatric Nephrology