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Hyperemesis gravidarum — MCCQE Part 1 MCQ

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ModerateNausea/VomitingHyperemesis gravidarumMCCQE Part 1

A 28-year-old G1P0 at 14 weeks has severe nausea, unable to tolerate fluids x 3 days, 5% weight loss, urine ketones 3+. TSH 0.1 with mildly elevated fT4. Most appropriate management?

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Correct answer: BIV fluids, antiemetics (ondansetron/dimenhydrinate), and thiamine

Hyperemesis gravidarum: IV fluids + antiemetics + thiamine (prevent Wernicke's). Suppressed TSH/elevated fT4 = gestational thyrotoxicosis from hCG cross-reactivity — transient, does NOT need antithyroid treatment.

Reference: SOGC NVP Guideline