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Pre-gestational DM and congenital anomalies — MCCQE Part 1 MCQ

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HardPregnancy ComplicationsPre-gestational DM and congenital anomaliesMCCQE Part 1

A 40-year-old G3P2 at 16 weeks has T1DM with pre-pregnancy HbA1c 80 mmol/mol and retinopathy. Which organ system is at highest risk of congenital anomaly?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Cardiovascular (congenital heart defects)

Pre-gestational DM with poor control: cardiac malformations most common category. Diabetes Canada: achieve HbA1c <48 mmol/mol before conception. Detailed fetal echo at 20-22 weeks for all pre-gestational DM.

Reference: Diabetes Canada / SOGC Pregnancy