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Phaeochromocytoma — MCCQE Part 1 MCQ

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HardHypertensionPhaeochromocytomaMCCQE Part 1

A 34-year-old woman has episodic palpitations, diaphoresis, severe headaches, and paroxysmal HTN (210/120). Urinary catecholamines/metanephrines markedly elevated. CT: 4cm right adrenal mass. Most appropriate preoperative management?

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Correct answer: A — Alpha-blockade with phenoxybenzamine for 10-14 days before surgery

Phaeochromocytoma: preop alpha-blockade for 10-14 days mandatory. Beta-blockers NEVER before adequate alpha-blockade — unopposed alpha stimulation causes hypertensive emergency.

Reference: Endocrine Society / Canadian practice