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Rhinocerebral mucormycosis — MCCQE Part 1 MCQ

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HardFacial PainRhinocerebral mucormycosisMCCQE Part 1

A 52-year-old woman with poorly controlled T2DM has right-sided facial pain, purulent nasal discharge, and black eschar on the nasal turbinate. Fever 39.5C, periorbital oedema. Most likely diagnosis?

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Correct answer: D — Mucormycosis (rhinocerebral zygomycosis)

Poorly controlled DM + black mucosal eschar + orbital involvement = rhinocerebral mucormycosis. Life-threatening: requires urgent surgical debridement + IV amphotericin B + glycaemic control. Mortality >50% if delayed.

Reference: Infectious Diseases Society / Canadian practice