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Rh alloimmunization prevention — MCCQE Part 1 MCQ

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ModeratePregnancy CareRh alloimmunization preventionMCCQE Part 1

A 27-year-old Rh-negative pregnant woman at 28 weeks gestation has a negative antibody screen. The father is Rh-positive. Which of the following is the most appropriate management?

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Correct answer: C — Administer antenatal Rh immunoglobulin according to Canadian prenatal practice

Rh-negative unsensitized pregnant patients should receive Rh immunoglobulin prophylaxis during pregnancy and after sensitizing events, with postpartum dosing if the infant is Rh-positive. Rh-positive mothers do not need anti-D prophylaxis. The aim is prevention of haemolytic disease in current and future pregnancies.

Reference: SOGC Rh alloimmunization guidance; Canadian Blood Services perinatal resources