Spontaneous bacterial peritonitis — MCCQE Part 1 MCQ
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Correct answer: E — Intravenous third-generation cephalosporin and albumin in selected high-risk patients
Ascitic neutrophils at or above 250 cells/mm3 diagnose spontaneous bacterial peritonitis and require immediate antibiotics. Lactulose may treat encephalopathy but does not treat the infection. Albumin is considered in patients at renal risk, and NSAIDs should generally be avoided in cirrhosis.
Reference: Canadian Association for the Study of the Liver; AASLD guidance used in Canadian practice