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Anaphylaxis — MCCQE Part 1 MCQ

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ModerateAllergic Reactions and AtopyAnaphylaxisMCCQE Part 1

A 16-year-old develops generalized urticaria, lip swelling, wheeze and dizziness 10 minutes after eating peanuts. Blood pressure is 84/50 mmHg. Which of the following is the most appropriate immediate treatment?

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Correct answer: AIntramuscular epinephrine into the mid-anterolateral thigh

Anaphylaxis with airway and cardiovascular features requires immediate intramuscular epinephrine. Antihistamines, bronchodilators and corticosteroids are adjuncts and must not delay epinephrine. Tryptase is not needed to make the acute diagnosis in a classic exposure-related presentation.

Reference: Canadian Society of Allergy and Clinical Immunology anaphylaxis guidance