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Rh-negative pregnancy bleeding — MCCQE Part 1 MCQ

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EasyPregnancyRh-negative pregnancy bleedingMCCQE Part 1

A healthy woman at 26 weeks' gestation has no known pre-existing diabetes and has not yet been screened for gestational diabetes. According to Diabetes Canada's preferred two-step approach, which first test should be arranged now?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CPerform a nonfasting 50 g glucose challenge test now

Diabetes Canada recommends screening every pregnant patient without known pre-existing diabetes at 24 to 28 weeks. Its preferred two-step approach begins with a nonfasting 50 g glucose challenge test with plasma glucose measured one hour later. A positive screen is followed by a diagnostic 75 g oral glucose tolerance test. Risk factors may prompt earlier testing, but their absence does not remove the universal 24-to-28-week screen. Glycated haemoglobin alone and urine glucose are not substitutes. A one-step 75 g oral glucose tolerance test is an accepted alternative pathway, but postpartum-only testing would miss gestational diabetes during pregnancy.

Reference: Diabetes Canada Clinical Practice Guidelines, Diabetes and Pregnancy, https://guidelines.diabetes.ca/cpg/chapter36