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Nephrotic syndrome – pattern — RACP Paediatrics MCQ

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EasyNephrologyNephrotic syndrome – patternRACP Paediatrics

A 4-year-old has urine dipstick showing 4+ protein and no blood. Urine PCR is 800 mg/mmol. Serum albumin is 14 g/L. There is no hypertension and creatinine is normal. What is the urinalysis pattern?

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Correct answer: E — Nephrotic syndrome

Heavy proteinuria (>200 mg/mmol) without haematuria, with hypoalbuminaemia, normal BP, and normal renal function = nephrotic syndrome. In this age group (1-10 years), the most likely cause is minimal change disease.

Reference: RCH Melbourne – 2023 – Nephrotic Syndrome CPG; RACP Paediatric Curriculum – Nephrology