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CMPA – amino acid formula — RACP Paediatrics MCQ

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ModerateNeonatalCMPA – amino acid formulaRACP Paediatrics

The same infant does not tolerate the extensively hydrolysed formula (develops vomiting and diarrhoea within 24 hours of each attempt). What is the next formula option?

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Correct answer: AAmino acid formula

Amino acid formula (AAF, e.g., Neocate, EleCare) is indicated when eHF is not tolerated. AAF contains only individual amino acids with no intact protein or peptides, eliminating the possibility of allergic reaction to protein components. It is also first-line for severe CMPA presentations (FPIES, eosinophilic oesophagitis).

Reference: RCH Melbourne – 2023 – CMPA CPG; ASCIA – 2024