Empirical MRSA cover – high prevalence — RACP Paediatrics MCQ
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Correct answer: B — Empirical MRSA cover indicated
In communities with high MRSA prevalence (>10-15%), empirical MRSA cover should be considered for skin and soft tissue infections. Oral co-trimoxazole or clindamycin provides MRSA coverage. In remote Aboriginal communities, MRSA rates are high and empirical MRSA cover is standard practice. Adjust based on culture results.
Reference: Australian Therapeutic Guidelines – 2024; RCH Melbourne – 2023