pH impedance – GORD quantification — RACP Paediatrics MCQ

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HardGIpH impedance – GORD quantificationRACP Paediatrics

A 6-month-old with suspected GORD is being considered for investigation to quantify acid and non-acid reflux events and correlate them with symptoms. What is the gold standard investigation?

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Correct answer: B — 24-hour pH/impedance study

24-hour combined pH/impedance (pH/MII) study is the gold standard for quantifying GOR. It measures both acid (pH <4) and non-acid reflux episodes and their temporal correlation with symptoms (symptom index, symptom association probability). It is more sensitive than pH monitoring alone and is particularly useful in infants on acid suppression.

Reference: RCH Melbourne – 2023 – GOR CPG; RACP Paediatric Curriculum – GI