Rh HDN — RACP Paediatrics MCQ

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A term neonate with jaundice at 12 hours. Mother Rh-negative, baby Rh-positive. DAT strongly positive. Retics 15%. What is the diagnosis?

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Correct answer: E — Rh haemolytic disease

Early jaundice + strongly positive DAT + Rh incompatibility = Rh haemolytic disease. Management: intensive phototherapy, possible exchange transfusion, IVIg.

Reference: RCH Melbourne – 2023 – Neonatal HDN CPG