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iNO weaning — RACP Paediatrics MCQ

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ModerateNeonataliNO weaningRACP Paediatrics

Mild PPHN responded to iNO (SpO2 improved, FiO2 reduced). How should iNO be weaned?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CInhaled nitric oxide

Wean iNO gradually (5 ppm steps, then 1 ppm below 5 ppm). Abrupt discontinuation causes rebound vasoconstriction. Sildenafil may facilitate weaning.

Reference: RCH Melbourne – 2023 – PPHN CPG